Drug intelligence / Profile preview

pancreatin

Development stage
Approved
Lead developer
Changzhou Qianhong Biopharma
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes, Insulin and Analogs → Hormones & Growth Factors → Recombinant Proteins and Enzymes, Blood Coagulation Factors → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Pancreatin is a mixture of digestive enzymes, including amylase, lipase, and protease, primarily derived from the porcine pancreas. It is used as an enzyme replacement therapy for patients with exocrine pancreatic insufficiency (EPI), a condition where the pancreas fails to secrete sufficient enzymes for proper digestion. This deficiency is commonly associated with cystic fibrosis, chronic pancreatitis, pancreatectomy, or gastrointestinal bypass surgery. By supplementing these essential enzymes, pancreatin facilitates the hydrolysis of fats into fatty acids and glycerol, starches into dextrins and sugars, and proteins into peptides. This process restores normal digestion, improves nutrient absorption, and alleviates symptoms such as steatorrhea and abdominal pain. Changzhou Qianhong Biopharma is a key producer of pancreatin API for global markets.

Brand names
CreonPancreazePertzyeZenpepViokacePangrolPancrex
Other names
pancreatic enzymespancreatinum胰酶
02

Targets

CTRC (Chymotrypsin C)PRSS1 (Trypsin family)PNLIP (Pancreatic triacylglycerol lipase)AMY (Pancreatic alpha-amylase)

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