pancrelipase + esomeprazole

Pancrelipase + esomeprazole is a combination therapy used primarily in patients with exocrine pancreatic insufficiency, such as those with chronic pancreatitis or after pancreatectomy. Pancrelipase is a mixture of digestive enzymes (amylases, lipases, and proteases) that aid in the digestion of proteins, fats, and starches when the pancreas does not produce enough enzymes. Esomeprazole is a proton pump inhibitor that reduces gastric acid secretion by irreversibly inhibiting the H+, K+-ATPase enzyme on gastric parietal cells. The combination is often used because acid suppression by esomeprazole enhances the effectiveness of oral pancreatic enzyme replacement therapy by preventing degradation of enzymes in acidic gastric conditions[1][2][3][6].

Brand names

Pangestyme EC