Pancrelipase protease

Pancrelipase protease is a component of pancrelipase, which is a mixture of digestive enzymes used to treat exocrine pancreatic insufficiency. Specifically, pancrelipase protease refers to the protease enzymes within the pancrelipase mixture that help break down proteins during digestion. Pancrelipase protease is a mixture of proteolytic enzymes, primarily trypsin and chymotrypsin, that are extracted from porcine pancreatic glands. These enzymes proteolytically cleave peptide bonds and are involved in food digestion[2]. As part of pancrelipase, it works alongside lipases and amylases to help patients who cannot digest food normally due to pancreatic enzyme deficiency (exocrine pancreatic insufficiency)[1][3]. The protease component is essential for the breakdown of dietary proteins into smaller peptides and amino acids that can be absorbed by the body. This enzyme replacement therapy is crucial for patients with conditions like cystic fibrosis, chronic pancreatitis, or those who have undergone pancreatectomy, as it helps prevent malnutrition and improves nutrient absorption[3][5].

Brand names

Viokace

Other names

Proteolytic enzymesTrypsinChymotrypsinProtease component