Drug intelligence / Profile preview

Pankreatan

Development stage
Unknown
Lead developer
Nordmark Pharma
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Pankreatan is a porcine-derived pancreatic enzyme replacement therapy (PERT) developed and manufactured by Nordmark Pharma GmbH. It contains pancreatin, a biological mixture of essential digestive enzymes including lipase, amylase, and proteases. The drug is indicated for the treatment of pancreatic exocrine insufficiency (PEI), a condition where the pancreas does not produce enough enzymes to digest food properly. Pankreatan is formulated as enteric-coated hard capsules containing microtablets or pellets, designed to release enzymes in the small intestine to aid in the digestion of fats, carbohydrates, and proteins. It is available in various strengths, notably 40,000 Ph. Eur. units of lipase per capsule.

Brand names
Pankreatan
Other names
pancreatinpancreatic enzyme replacement therapyPERT40,000 Ph. Eur. units lipase
02

Targets

GehA (Triacylglycerol lipase GehA)AMY (Pancreatic alpha-amylase)

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