Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
pantoprazole + domperidone
- Development stage
- Phase 4
- Lead developer
- Ritz Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Pantz-DM is a combination oral tablet developed by Ritz Pharma, containing the proton pump inhibitor (PPI) pantoprazole and the dopamine antagonist domperidone. Pantoprazole works by irreversibly inhibiting the H+/K+-ATPase enzyme system (proton pump) in gastric parietal cells, thereby reducing gastric acid secretion. Domperidone acts as a peripheral dopamine D2 receptor antagonist with prokinetic properties, enhancing gastrointestinal motility and increasing lower esophageal sphincter pressure. This combination is primarily indicated for the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, and symptoms associated with gastroparesis, such as nausea and vomiting.
- Brand names
- Pantz-DM
- Other names
- pantoprazole/domperidone
02
Targets
DRD2 (Dopamine D2 Receptor)ATP4A (Potassium–transporting ATPase alpha chain 1)
Beyond the preview
Go deeper on pantoprazole + domperidone.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on pantoprazole + domperidone.