Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Pantorush-D + Pantorush-DSR
- Development stage
- Unknown
- Lead developer
- Acure Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Pantorush-D and Pantorush-DSR are fixed-dose combination products developed by Acure Pharma, containing the proton pump inhibitor (PPI) pantoprazole and the dopamine D2 receptor antagonist domperidone. Pantoprazole works by irreversibly inhibiting the gastric H+/K+ ATPase enzyme system (the proton pump) in parietal cells, thereby suppressing gastric acid secretion. Domperidone acts as a peripheral dopamine antagonist with prokinetic and antiemetic properties, enhancing gastrointestinal motility and reducing symptoms such as nausea and vomiting. This combination is primarily indicated for the treatment of gastroesophageal reflux disease (GERD), dyspepsia, and other acid-related disorders associated with upper gastrointestinal motility symptoms. Pantorush-DSR specifically utilizes a sustained-release formulation for the domperidone component to provide prolonged therapeutic effects.
- Other names
- pantoprazole + domperidone
02
Targets
ATP4A (Potassium–transporting ATPase alpha chain 1)
Beyond the preview
Go deeper on Pantorush-D + Pantorush-DSR.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Pantorush-D + Pantorush-DSR.