Drug intelligence / Profile preview

Pantothenic acid

Development stage
Unknown
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Pantothenic acid is a water-soluble B vitamin (vitamin B5) essential for human health. It is required for the synthesis of coenzyme A (CoA), which plays a central role in the metabolism of carbohydrates, proteins, and fats by enabling acyl group transfer reactions. Through its incorporation into CoA and acyl carrier protein (ACP), pantothenic acid is critical for energy production via the tricarboxylic acid cycle and for fatty acid synthesis. It also supports acetylcholine synthesis and participates in cellular processes such as signal transduction and enzyme activation/deactivation through acylation and acetylation reactions. Pantothenic acid may help protect cells against peroxidative damage by increasing glutathione levels[1][4][6][8]. Deficiency is rare but can be treated with supplementation; it is commonly included in multivitamin products.

Brand names
Panto-250Panto250Panto 250Concept ObIrospan 24/6 KitPregvitTandem Plus
Other names
Vitamin B5D-pantothenic acidPantothenateCalcium-pantothenatePantethineAntidermatitis vitamin
02

Targets

PANK (Pantothenate kinase)

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