Drug intelligence / Profile preview

Papaya

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Papaya, derived from the *Carica papaya* plant, is a natural product and nutraceutical known for its diverse biological activities. Its various preparations, such as fermented papaya preparation (FPP), leaf extracts, peel extracts, and seed extracts, exhibit antioxidant, anti-inflammatory, antiviral, anti-parasitic, and platelet-augmenting effects. These actions are attributed to its ability to scavenge reactive oxygen species, modulate immune responses, inhibit viral replication, stabilize cell membranes, and chelate iron, among other mechanisms. It is also being investigated for its potential cognitive enhancing properties.

Other names
Carica papayaCarica folia
02

Targets

KIT (c-KIT proto-oncogene receptor tyrosine kinase)PTAFR (Platelet-activating factor receptor)NS2B/NS3 protease (Dengue virus NS2B/NS3 serine protease)IL-6 (Interleukin 6)NS5 (Dengue virus nonstructural protein 5)

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