Drug intelligence / Profile preview

Papulex

Development stage
Phase 4
Lead developer
Sinclair
Modality
Small Molecules
Administration
Topical
01

Overview

Papulex is a dermocosmetic skincare product line specifically formulated for the management of acne-prone skin. It is a topical cosmetic range rather than a prescription pharmaceutical. The formulation typically utilizes a triple-action approach with three key active ingredients: nicotinamide (niacinamide), which provides anti-inflammatory properties; zinc PCA (Zincidone), which helps regulate sebum production; and an Anti-Bacterial Adhesive (ABA) technology (Defenskin) that prevents *Cutibacterium acnes* from adhering to skin cells. The product line includes various formats such as oil-free creams, cleansing gels, and lotions, aimed at reducing blemishes and controlling oiliness in mild to moderate acne. The brand was originally part of Sinclair IS Pharma's portfolio before being acquired by Alliance Pharma in 2015.

Brand names
Papulex
Other names
Nicotinamide plus antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid
02

Targets

SRD5A (Steroid 5-alpha-reductase)

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