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para-methoxymethamphetamine
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
para-Methoxymethamphetamine (PMMA), also known as P-MNA and 4-methoxy-N-methylamphetamine (4-MMA), is a synthetic psychoactive drug of the amphetamine and phenethylamine class. It acts primarily as a serotonergic agent with stimulant and hallucinogenic properties. PMMA is structurally related to paramethoxyamphetamine (PMA) and MDMA but is considered more toxic with a higher risk of fatal overdose. It has been found in tablets sold as "ecstasy" but produces less euphoria and more severe adverse effects than MDMA. The mechanism involves serotonin-norepinephrine release and monoamine oxidase inhibition. There are no accepted medical uses for PMMA; it is used recreationally as an illicit substance[1][2][6].
- Other names
- P-MNAPMMA4-methoxy-N-methylamphetamine4-MMApara-methoxymethamphetamine
02
Targets
SERT (Sodium-dependent serotonin transporter)NET (Norepinephrine Transporter)MAOA (Monoamine oxidase A)
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