Drug intelligence / Profile preview

paracetamol + ambroxol hydrochloride

Development stage
Unknown
Lead developer
Laksun Lifesciences
Modality
Small Molecules
Administration
Oral
01

Overview

Paracetamol + ambroxol hydrochloride is a fixed-dose combination pharmaceutical product developed and distributed by Laksun Lifesciences. It combines paracetamol (acetaminophen), a widely used analgesic and antipyretic, with ambroxol hydrochloride, a mucolytic and secretolytic agent. Paracetamol provides symptomatic relief from pain and fever by inhibiting prostaglandin synthesis, primarily through the inhibition of cyclooxygenase (COX) enzymes in the central nervous system. Ambroxol hydrochloride facilitates the clearance of respiratory secretions by reducing mucus viscosity and stimulating the production of pulmonary surfactant. This combination is primarily indicated for the treatment of respiratory tract conditions associated with productive cough, congestion, and fever, such as the common cold and bronchitis. It is typically formulated as an oral tablet for immediate release.

Other names
paracetamol + ambroxol hclParacetamol Ambroxol HCl tablets
02

Targets

SCN10A (Sodium channel protein type X alpha subunit)PGHS-1 (Prostaglandin G/H Synthase 1)COX-3 (Prostaglandin-endoperoxide synthase 1 variant (Cyclooxygenase-3))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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