Drug intelligence / Profile preview

paracetamol + caffeine + chlorphenamine + artificial cow-bezoar

Development stage
Unknown
Lead developer
Anhui Huayuan Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Anka Huangmin Capsules (氨咖黄敏胶囊) is a widely used over-the-counter (OTC) compound cold medication in China. It is a fixed-dose combination containing paracetamol (acetaminophen), caffeine, chlorphenamine maleate, and artificial cow-bezoar. Paracetamol acts as an antipyretic and analgesic by inhibiting prostaglandin synthesis. Caffeine is a central nervous system stimulant that enhances the antipyretic and analgesic effects of paracetamol while mitigating drowsiness. Chlorphenamine maleate is a first-generation antihistamine that relieves allergy-like symptoms such as runny nose, nasal congestion, and sneezing. Artificial cow-bezoar provides additional antipyretic and sedative properties. The combination is indicated for the temporary relief of symptoms associated with the common cold and influenza, including fever, headache, sore throat, nasal congestion, and muscle aches. Shanghai Huayuan Anhui Renji Pharmaceutical is one of the approved manufacturers and distributors of this generic formulation.

Brand names
ConbaDadisukeDefeierHaoyishengSanjing三精康恩贝得菲尔好医生大地速克
Other names
Anka HuangminAnka Huangmin CapsulesAnka Huangmin JiaonangAnkahuangminAnkahuangmin CapsulesParacetamol, Caffeine, Artificial Cow-bezoar and Chlorphenamine Maleate Capsulesparacetamol + caffeine + chlorpheniramine + artificial bezoarparacetamol + caffeine + chlorpheniramine maleate + artificial cow-bezoar氨咖黄敏氨咖黄敏胶囊速效伤风胶囊
02

Targets

ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)ADORA2B (Adenosine A2B receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HRH1 (Histamine H1 Receptor)

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