Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
paracetamol + chlorphenamine
- Development stage
- Unknown
- Lead developer
- Abiogen
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Paracetamol + chlorphenamine is a fixed-dose combination medication comprising the analgesic and antipyretic paracetamol (acetaminophen) and the first-generation H1-antihistamine chlorphenamine (chlorpheniramine) maleate. Paracetamol exerts its effects primarily through the inhibition of prostaglandin synthesis in the central nervous system, reducing pain and fever. Chlorphenamine acts as a competitive antagonist at the H1 histamine receptor, alleviating symptoms of allergic reactions and the common cold, such as rhinorrhea and sneezing. This combination is widely utilized as an over-the-counter (OTC) treatment for symptomatic relief of cold and flu symptoms, including headache, fever, and nasal congestion.
- Brand names
- Andol S
- Other names
- paracetamol + chlorphenamine maleateacetaminophen + chlorpheniramineparacetamol + chlorpheniramine
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)COX-3 (Mitochondrially encoded cytochrome c oxidase subunit 3)HRH1 (Histamine H1 Receptor)mAChR (Muscarinic acetylcholine receptors)
Beyond the preview
Go deeper on paracetamol + chlorphenamine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on paracetamol + chlorphenamine.