paracetamol + chlorpheniramine maleate + phenylephrine

Paracetamol + chlorpheniramine maleate + phenylephrine is an approved oral small-molecule combination drug used to treat symptoms of the common cold, influenza, and allergic rhinitis, including nasal congestion, fever, headache, body aches, and sinus pressure. It contains three active ingredients: paracetamol (acetaminophen), an analgesic and antipyretic that inhibits prostaglandin synthesis in the central nervous system to relieve pain and reduce fever; phenylephrine, a sympathomimetic decongestant that stimulates alpha-1 adrenergic receptors to constrict blood vessels in the nasal mucosa, thereby relieving nasal congestion and sinus pressure; and chlorpheniramine maleate, a first-generation antihistamine that blocks H1 histamine receptors to alleviate allergy symptoms such as sneezing, runny nose, watery eyes, and itching.

Brand names

Alex P PaedAlerfriColdicareCoriminic PCozy-KidFebrex PlusKoldbayMaxtra PSneezdocSolvin ColdSumo Cold PcfTagorylTusQ-PZincold

Other names

acetaminophen + chlorpheniramine maleate + phenylephrineparacetamol + chlorpheniramine + phenylephrineparacetamol + chlorpheniramine maleate + phenylephrine hydrochlorideparacetamol, chlorpheniramine maleate, and phenylephrineparacetamol, chlorpheniramine maleate, and phenylephrine hydrochloride