Drug intelligence / Profile preview

paracetamol + mefenamic acid

Development stage
Phase 2
Lead developer
Amvia Biotech
Modality
Small Molecules
Administration
Oral
01

Overview

BITUGESIC MF/DS is a combination oral suspension containing paracetamol (acetaminophen) and mefenamic acid, developed by Amvia Biotech. Paracetamol is a widely used analgesic and antipyretic that acts primarily by inhibiting prostaglandin synthesis in the central nervous system. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) belonging to the fenamate class, which works by inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the production of inflammatory prostaglandins. This combination is formulated as a suspension (available in standard and double strengths) to facilitate administration in pediatric patients for the treatment of mild to moderate pain, fever, and inflammatory conditions such as dysmenorrhea.

Brand names
BITUGESIC MF/DSBITUGESIC MFBITUGESIC DS
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)

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