Drug intelligence / Profile preview

paracetamol + phenylephrine (Bristol Laboratories)

Development stage
Unknown
Lead developer
Bristol Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

Max Flu Strength is a combination small molecule pharmaceutical product developed and manufactured by Bristol Laboratories for the symptomatic relief of cold and flu. It contains two active ingredients: paracetamol (acetaminophen) and phenylephrine hydrochloride. Paracetamol serves as a non-salicylate analgesic and antipyretic, primarily acting through the inhibition of prostaglandin synthesis in the central nervous system to alleviate pain and reduce fever. Phenylephrine is a sympathomimetic amine that acts as a selective alpha-1 adrenergic receptor agonist, inducing vasoconstriction in the nasal mucosa to relieve congestion. The product is approved for the relief of aches, pains, headache, nasal congestion, and sore throat associated with influenza and the common cold.

Brand names
Max Flu Strength
Other names
Paracetamol + Phenylephrine
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)ADRA1A (α1A)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ADRA1D (α1D)ADRA1B (α1B)

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