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Drug intelligence / Profile preview
paracetamol + phenylephrine (Bristol Laboratories)
- Development stage
- Phase 1
- Lead developer
- Bristol Laboratories
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Max Flu Strength is a combination small molecule pharmaceutical product developed and manufactured by Bristol Laboratories for the symptomatic relief of cold and flu. It contains two active ingredients: paracetamol (acetaminophen) and phenylephrine hydrochloride. Paracetamol serves as a non-salicylate analgesic and antipyretic, primarily acting through the inhibition of prostaglandin synthesis in the central nervous system to alleviate pain and reduce fever. Phenylephrine is a sympathomimetic amine that acts as a selective alpha-1 adrenergic receptor agonist, inducing vasoconstriction in the nasal mucosa to relieve congestion. The product is approved for the relief of aches, pains, headache, nasal congestion, and sore throat associated with influenza and the common cold.
- Brand names
- Max Flu Strength
- Other names
- Paracetamol + Phenylephrine
02
Targets
ADRA1A (α1A)ADRA1B (α1B)ADRA1D (α1D)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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