paracetamol + propyphenazone + caffeine

Paracetamol + propyphenazone + caffeine is an oral fixed-dose, non-opioid analgesic-antipyretic combination used for short-term treatment of headache, migraine, fever, dysmenorrhea, toothache, and other acute pain states. It combines paracetamol, a centrally acting analgesic and antipyretic; propyphenazone, a pyrazolone analgesic with cyclooxygenase-inhibitory and anti-inflammatory activity; and caffeine, an adenosine-receptor antagonist used as an analgesic adjuvant. A common Saridon tablet formulation contains paracetamol 250 mg, propyphenazone 150 mg, and caffeine 50 mg, although strengths vary among brands and markets. The exact three-component combination is documented as an analgesic and antipyretic drug combination in the peer-reviewed literature and is marketed in several countries, including as Saridon. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/33221830/))

Brand names

Bodrex MigraCaffetin LightSaridonSaridon-NSariphezon

Other names

acetaminophen + caffeine + propyphenazonecaffeine + paracetamol + propyphenazoneparacetamol + caffeine + propyphenazonepropyphenazone + paracetamol + caffeinepropyphenazone/paracetamol/caffeine