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Paracetamol Uniflash
- Development stage
- Unknown
- Lead developer
- Unither Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Buccal, Oromucosal
01
Overview
Paracetamol Uniflash is a novel buccal transmucosal formulation of paracetamol (acetaminophen) developed by Unither Pharmaceuticals for the treatment of acute pain. Utilizing the proprietary Uniflash technology, the drug is delivered as a 125 mg/1.25 mL oromucosal solution designed for rapid absorption through the oral mucosa. This delivery route bypasses hepatic first-pass metabolism, aiming to achieve efficacy and speed of action comparable to intravenous administration. It has been evaluated in Phase 3 clinical trials for acute pain following tooth extraction, demonstrating a pharmacokinetic profile that supports its use as a fast-acting analgesic.
- Brand names
- Paracetamol Uniflash
- Other names
- paracetamolacetaminophen
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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