Drug intelligence / Profile preview

paraffin emollient cream

Development stage
Unknown
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Paraffin emollient cream is a topical skin preparation containing a combination of liquid paraffin and white soft paraffin as its main active ingredients. It is used primarily as an occlusive moisturizer to treat or prevent dry, rough, scaly, or itchy skin conditions such as eczema, ichthyosis, pruritus of the elderly, and minor skin irritations. The mechanism of action involves forming an oily layer on the surface of the skin that traps water in the epidermis (outer layer), thereby reducing transepidermal water loss and maintaining hydration. This helps relieve dryness and leaves the skin feeling softer and more comfortable[5][6][7]. Paraffin-based emollients are also used to restore barrier function in atopic eczema by preventing entry of irritants/allergens/bacteria[4]. These creams are generally unperfumed medical moisturizers distinct from cosmetic moisturizers.

Brand names
EmodermLiquid ParaffinLiquid Parafin
Other names
liquid paraffin and white soft paraffin creamliquid paraffin + white soft paraffinemulsifying ointment with white soft paraffin and liquid paraffin

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