Paremyd

Paremyd is a sterile ophthalmic solution used as a topical mydriatic combination product for ophthalmic use. It contains two active ingredients: hydroxyamphetamine hydrobromide (1%) and tropicamide (0.25%). Hydroxyamphetamine hydrobromide is an indirectly-acting sympathomimetic agent that causes the release of endogenous norepinephrine from adrenergic nerve terminals in the eye, resulting in pupil dilation (mydriasis). Tropicamide is an anticholinergic (parasympatholytic) agent that blocks cholinergic stimulation of the iris sphincter muscle and ciliary muscle, leading to further pupil dilation and partial paralysis of accommodation (cycloplegia). The combination provides rapid onset mydriasis within 15 minutes, with maximum effect at 60 minutes; effects typically last 3 hours with recovery beginning at about 90 minutes and complete recovery usually within 6–8 hours. Paremyd is primarily indicated for use in routine diagnostic procedures requiring short-term pupil dilation[1][2][4][5][6].

Brand names

Paremyd

Other names

hydroxyamphetamine hydrobromide and tropicamidehydroxyamphetamine-tropicamidetropicamide/hydroxyamfetamine