Drug intelligence / Profile preview

parietaria judaica pollen extract

Development stage
Phase 1
Lead developer
Dome
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous, Sublingual, Oral
01

Overview

**Parietaria judaica pollen extract** is a standardized allergen extract derived from *Parietaria judaica* pollen and used as allergen-specific immunotherapy for **Parietaria-induced respiratory allergy**, especially allergic rhinitis, rhinoconjunctivitis, and mild allergic asthma in sensitized patients. It is administered as either **subcutaneous immunotherapy** or **sublingual immunotherapy** in the cited clinical literature. Its therapeutic mechanism is immune tolerance induction: repeated exposure to the causative pollen allergens is intended to desensitize patients, reduce clinical reactivity during pollen season, and modulate allergen-specific immune responses, including changes in immunoglobulin profiles and skin-test reactivity. Publicly cited development includes a multicenter open trial sponsored by **ROXALL Medizin** evaluating depot subcutaneous immunotherapy, along with randomized placebo-controlled studies and publication reports supporting clinical efficacy and tolerability in Parietaria-associated rhinoconjunctivitis with or without mild asthma.

Other names
Parietaria judaica pollen extractParietaria pollen vaccineParietaria judaica extractP. judaica pollen extract
02

Targets

IgE (Immunoglobulin E)

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