pasiniazid

**Pasiniazid** is a defined 1:1 molecular salt/complex of isoniazid and para-aminosalicylic acid used as an oral antitubercular drug. It dissociates in the gastrointestinal tract to deliver isoniazid, which is activated by mycobacterial catalase-peroxidase KatG and inhibits InhA-dependent mycolic-acid synthesis, and para-aminosalicylic acid, an antifolate prodrug whose active metabolites inhibit mycobacterial dihydrofolate reductase. It has been used in multidrug regimens for pulmonary tuberculosis, including retreatment regimens. ([medchemexpress.com](https://www.medchemexpress.com/Pasiniazid.html))

Brand names

DipasicFintozidJieheqingNidrapasParasal INHPascidaberPAS-HidracidaPashain

Other names

4-amino-2-hydroxybenzoic acid;pyridine-4-carbohydrazideIsoniazid 4-aminosalicylateIsoniazid4-aminosalicylateIsoniazid-4-aminosalicylateisoniazid aminosalicylateIsoniazid p-aminosalicylateIsonicotinic acid hydrazide 4-aminosalicylateIsonicotinic acid hydrazide p-aminosalicylateIsonicotinohydrazide 4-amino-2-hydroxybenzoateIsonicotinohydrazide4-amino-2-hydroxybenzoateIsonicotinohydrazide-4-amino-2-hydroxybenzoateParaniazidep-aminosalicylic acid isonicotinyl hydrazidePasiniazidaPasiniazidePasiniazidum