Drug intelligence / Profile preview

pasteurized akkermansia muciniphila

Development stage
Unknown
Lead developer
Danone
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Pasteurized Akkermansia muciniphila is a non-viable, heat-treated form of the beneficial gut bacterium *Akkermansia muciniphila*. It is classified as a postbiotic or next-generation probiotic and is being investigated as both a pharmaceutical agent and a dietary supplement. The pasteurization process inactivates the bacteria but preserves key bioactive components, such as the outer membrane protein Amuc_1100, which are believed to be responsible for its therapeutic effects. These effects include strengthening the gut barrier, reducing inflammation, and improving metabolic health. [1, 4] Clinical and preclinical studies are exploring its potential in managing metabolic syndrome, insulin resistance, type 2 diabetes, obesity, and metabolic dysfunction-associated steatotic liver disease (MASLD). [5] Several companies, including A-Mansia Biotech and Leeuwenhoek Laboratories, are developing it as a therapeutic, while The Akkermansia Company markets it as a dietary supplement for gut health and weight management. [3, 11]

Brand names
Akkermansia muciniphila MucT™
Other names
Akkermansia muciniphila postbiotic
02

Targets

TLR2 (Toll-like Receptor 2)

Beyond the preview

Go deeper on pasteurized akkermansia muciniphila.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on pasteurized akkermansia muciniphila.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call