Drug intelligence / Profile preview

patrinia villosa extract

Development stage
Preclinical
Lead developer
Natural Solution
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Patrinia villosa extract is a botanical extract derived from the whole plant *Patrinia villosa* (Thunb.) Juss, a traditional Chinese medicinal herb (Bai Jiang Cao) belonging to the Valerianaceae or Caprifoliaceae family. The extract contains a complex mixture of active constituents, including isovitexin, isoorientin, iridoids, triterpenoids, saponins, and luteolin. It is primarily researched for its anti-inflammatory, anti-bacterial, and anti-cancer properties, particularly in the context of colorectal cancer where it has been shown to inhibit the VEGF/p38MAPK/HSP27 signaling pathway. Beyond its medicinal potential, it is also utilized as a cosmetic ingredient for skin conditioning.

Brand names
Patrinia Extract-NS
Other names
patrinia villosa extractBai Jiang Cao extractPV extract
02

Targets

VEGFA (Vascular endothelial growth factor A)HSPB1 (Heat shock protein beta-1)MAPK14 (p38 mitogen-activated protein kinase alpha)

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