PB03

PB03 (marketed as Oncosens) is a topical therapeutic product developed by Prospera Biotech, a spin-off from the Miguel Hernández University of Elche. It is specifically formulated to manage skin sensitivity and discomfort, such as itching, burning, and tingling, in patients undergoing chemotherapy. The product utilizes Prospera's proprietary technology to modulate Transient Receptor Potential (TRP) channels, specifically targeting the TRPV1 channel on sensory nerve endings in the skin. By inhibiting the over-activation of these channels caused by chemotherapeutic agents, PB03 helps restore skin comfort and barrier function. It is marketed as a dermocosmetic solution for chemotherapy-induced skin toxicity and is part of a pipeline of neuro-active products designed to treat peripheral sensory disorders.

Brand names

Oncosens