PB04

PB04 is a topical neurocosmetic product developed by Prospera Biotech for the management of intimate sensitivity, vaginal dryness, and itching. Marketed under the brand name Vagisens, it utilizes a proprietary peptide-based technology (HM-peptides) designed to modulate the activity of Transient Receptor Potential (TRP) channels, specifically the TRPV1 channel, on sensory nerve endings in the vulvovaginal mucosa. By desensitizing these channels, PB04 helps to alleviate the discomfort, burning, and itching sensations associated with vaginal hypersensitivity. It is part of a line of sensory-targeted products developed by Prospera Biotech, a spin-off from the Miguel Hernández University of Elche, focusing on neuro-dermatology and the treatment of skin and mucosal discomfort through sensory neuron modulation.

Brand names

Vagisens