PB220

PB220 is a recombinant enzyme product developed by Proteos Biotech, consisting of Collagenase G and Collagenase H derived from *Clostridium histolyticum*. Produced via recombinant DNA technology in bacterial systems, it functions as a proteolytic enzyme that specifically targets and degrades non-functional or amorphous collagen fibers within the extracellular matrix. This mechanism facilitates the remodeling of connective tissue, making it effective for treating pathological collagen accumulation in scars, post-surgical fibrosis, and striae (stretch marks). Marketed under the PBSerum brand, it is also utilized in aesthetic medicine for facial, periocular, and hand rejuvenation to improve skin health and texture. The enzyme is typically provided in a lyophilized form to maintain stability and activity without the need for preservatives.

Brand names

PBSerum

Other names

Collagenase G/HCollagenases G&HRecombinant Collagenase G/HCollagenase G/H PB220