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PB2202 is a human biologic therapeutic candidate developed by PB Immune Therapeutics for the treatment of Graft-versus-Host Disease (GvHD). The drug is part of a pipeline focused on precision immunology, utilizing the company's proprietary ImmuneDict platform, which integrates single-cell transcriptomics and proteomics to identify novel therapeutic targets. PB2202 is designed to address the immune dysregulation characteristic of GvHD, a serious complication of hematopoietic stem cell transplantation. As of early 2024, the program is in early-stage clinical development, transitioning from preclinical studies to Phase 1.
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