Drug intelligence / Profile preview

PB718

Development stage
Preclinical
Lead developer
PegBio
Administration
Subcutaneous
01

Overview

PB718 is a biologic therapeutic developed by PEG Biosciences for the treatment of drug addiction, specifically opioid addiction, and the management of pain. It is designed to target opioid receptors in the brain to reduce and prevent the effects of opiates, mitigate withdrawal symptoms, and minimize patient discomfort during the detoxification process. As a next-generation therapeutic, PB718 aims to provide a dual-purpose solution for both chronic pain and substance use disorders by modulating opioid receptor activity to prevent relapse.

02

Targets

GLP1R (GLP-1R)GCGR (Glucagon receptor)MOR (Mu opioid receptor)

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