PBI-01011

PBI-01011 is an investigational botanical drug candidate developed by Phoenix Biotechnology, derived from an extract of *Nerium oleander*. It is specifically formulated for the treatment of neurodegenerative diseases and the mitigation of neuronal damage following ischemic stroke. Preclinical research, conducted in collaboration with institutions like Duke University, indicates that PBI-01011 exerts neuroprotective effects by inducing the expression of brain-derived neurotrophic factor (BDNF) and enhancing antioxidant activity within the brain. These actions help protect neurons from oxidative injury and neuroinflammation, which are key drivers of neurodegeneration. As a complex plant extract, it represents a botanical modality aimed at multi-target neuroprotection and is currently in exploratory development stages.