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PBI-04711
- Development stage
- Preclinical
- Lead developer
- Phoenix Biotechnology
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
01
Overview
PBI-04711 is a first-generation botanical extract developed by Phoenix Biotechnology, Inc. Derived from the oleander plant (*Nerium oleander*), it is uniquely processed to be free of cardiac glycosides, specifically excluding oleandrin to mitigate potential cardiotoxicity. The extract contains a concentrated mixture of oleander-derived triterpenes and is being investigated for its neuroprotective properties. Preclinical research suggests potential utility in treating neurodegenerative conditions by leveraging the bioactivity of triterpenoids without the narrow therapeutic index associated with traditional oleander extracts.
- Other names
- oleander-derived triterpene extractcardiac glycoside-free oleander extract
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