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PBI-1393 (also known as BCH-1393) is a small molecule immunomodulator designed to enhance Th1-type immune responses. Chemically identified as N,N-Dimethylaminopurine pentoxycarbonyl D-arginine, it acts by promoting the production of Th1-type cytokines, such as interferon-gamma (IFN-γ) and interleukin-2 (IL-2), and facilitating primary T-cell activation. Originally developed by BioChem Pharma and later associated with ProMetic BioSciences, the compound was investigated for its potential in immunotherapy, particularly for bolstering cellular immunity in the context of oncology and infectious diseases. It remains a research-stage compound and has not reached clinical approval.
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