PC-0061

PC-0061 is a long-acting microsphere injection formulation of **naltrexone**, a small molecule opioid receptor antagonist. Developed by **Changtai Pharmaceutical** (also known as **PharmaMax Corp**), it is specifically designed for the treatment of **opioid dependence** and **alcohol dependence**. The drug utilizes a microsphere delivery system to provide sustained release of the active ingredient over an extended period, typically one month, following a single intramuscular injection. This long-acting formulation aims to improve patient compliance and treatment outcomes by eliminating the need for daily oral dosing, which is a significant challenge in addiction recovery. Naltrexone works by competitively binding to mu-opioid receptors in the central nervous system, thereby blocking the euphoric and reinforcing effects of exogenous opioids and reducing alcohol cravings by modulating the brain's reward pathways.

Other names

naltrexone microspheresnaltrexone long-acting injection