Drug intelligence / Profile preview

PCV2-Mycoplasma dual vaccine

Development stage
Unknown
Lead developer
Boehringer Ingelheim
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The PCV2-Mycoplasma dual vaccine is a veterinary combination biologic designed to provide simultaneous protection against Porcine Circovirus Type 2 (PCV2) and *Mycoplasma hyopneumoniae* (M. hyo) in swine. PCV2 is the primary agent of Porcine Circovirus Associated Disease (PCVAD), which causes wasting and immunosuppression, while M. hyo is the causative agent of enzootic pneumonia, a chronic respiratory disease. These vaccines typically utilize a recombinant PCV2 capsid protein (ORF2) expressed in a baculovirus system and an inactivated M. hyo bacterin, often formulated with specialized adjuvants to enhance the immune response. By targeting two of the most significant pathogens in the Porcine Respiratory Disease Complex (PRDC), these dual vaccines reduce the number of injections required, improving animal welfare and labor efficiency on farms while significantly reducing lung lesions and viral shedding.

Brand names
Fostera PCV MHCircumvent PCV MPorcilis PCV MIngelvac CircoFLEXIngelvac MycoFLEXFLEXcombo
Other names
PCV2-M. hyo vaccinePCV-2-M. hyo vaccinePCV 2-M. hyo vaccinePorcine Circovirus Type 2-Mycoplasma Hyopneumoniae VaccinePCV2-Mycoplasma hyopneumoniae combination vaccinePCV-2-Mycoplasma hyopneumoniae combination vaccinePCV 2-Mycoplasma hyopneumoniae combination vaccine
02

Targets

Mycoplasma hyopneumoniae surface membrane and adhesin antigensPCV2 Cap (Porcine circovirus type 2 capsid protein)

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