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Peanut Immunotherapy (University Hospital, Geneva)
- Development stage
- Unknown
- Lead developer
- Hôpitaux Universitaires de Genève
- Administration
- Subcutaneous
01
Overview
Peanut Immunotherapy (University Hospital, Geneva) is an allergen-specific immunotherapy (AIT) consisting of a subcutaneous injection of peanut extract. Developed by the University Hospital, Geneva, this treatment was investigated in a Phase 1/2 pilot study (NCT00107796) to evaluate its safety and efficacy in children and adults with persistent peanut allergy. The protocol involved bi-weekly injections over a three-month period. The therapy aims to induce immunological tolerance by modulating the immune system's response to peanut proteins, specifically by promoting the production of regulatory T cells and allergen-specific IgG4 antibodies while reducing IgE-mediated mast cell and basophil activation.
- Other names
- Injected peanut immunotherapyPeanut extract immunotherapy
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