Drug intelligence / Profile preview

PEARL-201

Development stage
Preclinical
Lead developer
PearlsInMires
Modality
Small Molecules
01

Overview

PEARL-201 is a preclinical-stage small molecule therapeutic being developed by PearlsInMires for the treatment of alopecia. It is designed to target the androgen receptor (AR) and dihydrotestosterone (DHT) signaling pathway, which plays a critical role in the miniaturization of hair follicles in androgenetic alopecia. By modulating these androgenic components, PEARL-201 aims to prevent hair loss and potentially promote hair regrowth. The program is currently in the preclinical phase, with the developer aiming to complete patent applications for this and related assets by 2025.

02

Targets

AR (Adrenergic receptors)

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