pearl millet grain ethanol extract

Pearl millet grain ethanol extract is an ethanol-based extract derived from the grains of *Pennisetum glaucum* (pearl millet). It contains a rich spectrum of bioactive compounds, notably phenolics (e.g., coumarins, flavonoids, tannins, steroids), with proven **anti-hyperlipidemic, hypoglycemic, hepatoprotective, and anti-inflammatory effects** in animal models. The extract works mainly by modulating metabolic and inflammatory pathways, likely through inhibition of carbolytic enzymes (e.g., α-glucosidase), reduction of gluconeogenesis, improvement of insulin resistance, reduction of pro-inflammatory cytokines (IL-6, TNF-α, CRP), and antioxidant activity. Pearl millet polyphenols are posited to regulate glucose transporters (GLUT) and lipid metabolism, contributing to dose-dependent reductions in body weight, serum triglycerides, cholesterol, and blood glucose in rodents fed a high-fat diet[1][3][5][9]. This extract is being investigated for functional food, nutraceutical, and potential therapeutic applications related to metabolic and liver diseases.

Other names

Pennisetum glaucum ethanol extractMPG ethanol extractmillet phenolic ethanol extract