pectin

Pectin is a heterogeneous plant-derived polysaccharide and soluble dietary fiber composed mainly of galacturonic acid-rich chains with variable methyl esterification and neutral sugar side chains. In the provided public sources, it is being investigated as a therapeutic nutritional adjunct rather than as a conventional pharmaceutical active ingredient, particularly for improving tolerance to enteral nutrition and reducing diarrhea in critically ill patients, and has also been studied preclinically for anti-inflammatory, lipid-lowering, and anticancer effects. Its proposed mechanisms are multifactorial and formulation/source dependent, including increasing luminal viscosity and semi-solidifying enteral feeds, fermentation by gut microbiota to short-chain fatty acids, and direct modulation of innate immune signaling such as Toll-like receptor 2 and Toll-like receptor 4 pathways, with downstream suppression of inflammatory cytokines including interleukin-6. Because \"pectin\" is a broad, structurally variable natural substance rather than a single well-defined molecular entity, activity can differ substantially by source and preparation such as citrus, orange, apple, or modified pectin.

Brand names

PX pectin

Other names

果胶citrus pectinorange pectinapple pectinmodified pectinmodified citrus pectin