pediococcus acidilactici SWU-HY34

Pediococcus acidilactici SWU-HY34 is a specific strain of the species Pediococcus acidilactici, a Gram-positive, facultatively anaerobic, lactic acid bacterium commonly isolated from fermented foods. Strains of P. acidilactici are recognized for their probiotic properties, which include high survivability in the gastrointestinal environment, strong adhesion to intestinal epithelial cells, γ-hemolytic activity, and resistance to certain antibiotics typical of lactic acid bacteria. These strains exert health-promoting effects mainly by producing lactic acid and bacteriocins (notably pediocins), which inhibit pathogenic bacteria, as well as by modulating immune responses. Research demonstrates anti-inflammatory activity, downregulation of pro-inflammatory mediators such as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), and suppression of cytokines like IL-1β and IL-6, primarily via modulation of nuclear factor-κB (NF-κB), mitogen-activated protein kinase (MAPK), and activator protein-1 (AP-1) signaling pathways. Clinical and animal studies on P. acidilactici strains (including other specific isolates) suggest potential benefits for gastrointestinal health, metabolic syndrome (such as hyperglycemia and hypercholesterolemia), and possibly as a therapeutic adjunct for various inflammatory diseases. SWU-HY34 refers to a particular isolate, with properties generally in line with the species, although specific published information about SWU-HY34 itself is limited[1][2][3][4][5].

Other names

pediococcus acidilactici SWU-HY34