Drug intelligence / Profile preview

Pegorion

Development stage
Phase 4
Lead developer
Orion
Modality
Small Molecules
Administration
Oral
01

Overview

Pegorion is an osmotic laxative containing polyethylene glycol 4000 (macrogol 4000) without electrolytes, developed by Orion Corporation. It is indicated for the treatment of both acute and chronic constipation. The drug works through an osmotic mechanism, where the high molecular weight polymer retains water within the intestinal lumen. This increases stool volume and softens its consistency, which in turn stimulates colonic peristalsis and facilitates easier evacuation. Pegorion is specifically formulated without electrolytes (such as sodium or potassium salts), which can improve its taste profile and make it a suitable option for patients who need to limit their salt intake or who find electrolyte-containing solutions unpalatable. It is widely available as an over-the-counter medication in Finland and other European markets.

Brand names
Pegorion
Other names
polyethylene glycol 4000macrogol 4000macrogol4000macrogol-4000

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