Drug intelligence / Profile preview

pegylated consensus interferon mutant

Development stage
Unknown
Lead developer
三元基因
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Parenteral
01

Overview

A PEGylated recombinant protein biologic developed by Beijing Tri-Prime Gene Pharmaceutical for the treatment of chronic hepatitis B. It is a long-acting interferon mutant designed to provide prolonged interferon-alpha activity and enhanced antiviral effects compared to standard formulations. As an IFNAR agonist, it induces an innate antiviral immune response and acts as an immunostimulant. The drug is currently in Phase 1 clinical development in China, where studies have evaluated its safety, tolerability, and pharmacokinetic/pharmacodynamic profiles in healthy subjects and patients with chronic hepatitis B.

Other names
新型PEG集成干扰素突变体注射液Novel PEGylated integrated interferon mutant injectionNovel PEG-Consensus Interferon Mutant Injectionpegylated integrated interferon mutant
02

Targets

IFNAR (Immune system modulation via type I interferon receptor)

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