Drug intelligence / Profile preview

Peking Univ. FGFR4 compound 24

Development stage
Preclinical
Lead developer
Peking University
01

Overview

Peking Univ. FGFR4 compound 24: sourced facts only. name: "Representative compounds 24 and 30 exhibited potent FGFR4 inhibition and high selectivity among kinases." [PMID:35549181]; target: "Representative compounds 24 and 30 exhibited potent FGFR4 inhibition and high selectivity among kinases." [PMID:35549181]; developer: "State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School, Peking University, Shenzhen 518055, China." [PMID:35549181]; stage: "Western blot analysis showed that compounds 24 and 30 significantly inhibited the FGF19/FGFR4 signaling pathway in HuH-7 cells and effectively suppressed the proliferation of HuH-7 HCC cells and MDA-MB-453 breast cancer cells." [PMID:35549181]

02

Targets

FGFR4 (Fibroblast growth factor receptor 4)

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