Drug intelligence / Profile preview

pelargonidin

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Pelargonidin is a naturally occurring **anthocyanidin**—a plant pigment notably responsible for orange to red colors in various flowers and fruits. It belongs to the flavonoid class, specifically 7-hydroxyflavonoids, and contains hydroxy groups at the 3, 5, 7, and 4' positions of the flavylium backbone[1][5][7]. **Pelargonidin is primarily found in red geraniums, and fruits such as strawberries, black raspberries, radishes, and sour cherries**[1][7]. It serves as a plant metabolite with notable **antioxidant properties** and has been studied for potential antidiabetic and anticancer effects, mainly through radical scavenging and inhibition of reactive oxygen species, though it is not an approved pharmaceutical drug[2]. Its mechanism of action is primarily related to non-specific antioxidant activity and possibly the inhibition of enzymes like nitric oxide synthase (NOS)[2].

Other names
pelargonidinpelargonidol3,5,7-trihydroxy-2-(4-hydroxyphenyl)-2H-chromen-2-ylium
02

Targets

ARE (Antioxidant response element)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)

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