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Pendulum Akkermansia
- Development stage
- Unknown
- Lead developer
- Pendulum Therapeutics
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Pendulum Akkermansia is a probiotic dietary supplement developed by Whole Biome (now Pendulum) that features the specific bacterial strain *Akkermansia muciniphila*. This next-generation probiotic is a mucin-degrading bacterium that naturally colonizes the intestinal mucus layer. The supplement is designed to support metabolic health by strengthening the intestinal barrier, modulating the gut microbiome, and improving metabolic functions such as glucose metabolism and weight management. Unlike many traditional probiotics, *A. muciniphila* is an anaerobic bacterium that plays a critical role in maintaining the gut lining. It is marketed as a commercial dietary supplement rather than a pharmaceutical drug.
- Brand names
- Pendulum Akkermansia
- Other names
- Akkermansia muciniphilaAkkermansia
02
Targets
MUC2 (Mucin-2)
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