Pennsaid (diclofenac)

Pennsaid is a brand name for a topical formulation of diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID). It is indicated for the treatment of pain and symptoms associated with osteoarthritis of the knee. The active ingredient, diclofenac sodium, works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the synthesis of prostaglandins—substances that mediate inflammation and pain. By reducing prostaglandin production at the site of application, Pennsaid provides localized relief from pain and inflammation without significant systemic absorption. The product is available as a clear or faintly colored solution intended for topical use only on the knees[1][2][4][5][6].

Brand names

Pennsaid

Other names

diclofenac sodium topical solution