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Pensa
- Development stage
- Unknown
- Lead developer
- Towa Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Pensa is a name associated with the **PENSA trial** (Prophylactic Effect of Candesartan and Lisinopril in Migraine), a landmark clinical study conducted by researchers at **St. Olavs Hospital** in Norway. The trial investigated the efficacy of two antihypertensive medications—**candesartan** (an angiotensin II receptor blocker) and **lisinopril** (an ACE inhibitor)—for the prophylactic treatment of migraine. Both drugs were found to significantly reduce the number of days with migraine compared to placebo. In the context of this research, 'Pensa' often refers to the specific generic formulations provided by **Pensa Pharma** (now part of Towa Pharma) that were used in the study. These medications are thought to work by modulating neurovascular pathways and neurogenic inflammation through the inhibition of the renin-angiotensin system.
- Brand names
- PensaCandesartan PensaLisinopril Pensa
- Other names
- PENSA study drugs
02
Targets
ACE (Angiotensin Converting Enzyme)AGTR1 (Angiotensin II Type-1 receptor)
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