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PEP-DC1

Development stage: Unknown
Modality: Dendritic Cell Vaccines → Immune Effector Cells → Other Cell Types → Cell Therapies, Vaccines & Immunotherapeutics
Administration: Intradermal (based On Standard Practice For Dendritic Cell Vaccines; Specific Route Not Explicitly Stated But Inferred From Context[1])

Overview

PEP-DC1 is an investigational personalized cancer vaccine composed of autologous dendritic cells pulsed with patient-specific peptides. These peptides are either detected or predicted in advance using integrated antigen discovery platforms. The vaccine is designed to stimulate the patient's immune system to recognize and attack tumor cells by presenting these personalized antigens via dendritic cells, which are potent antigen-presenting cells. The approach aims to enhance anti-tumor immunity in patients with high-grade gliomas and potentially other cancers[1].

Targets

pMHC-II (Peptide-major histocompatibility complex class II complex)pMHC-I (Peptide–MHC class I complex)

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