Drug intelligence / Profile preview

peppermint oil + caraway oil

Development stage
Unknown
Lead developer
Schwabe
Modality
Small Molecules
Administration
Oral
01

Overview

This is a fixed-dose herbal combination consisting of peppermint oil (Mentha x piperita L.) and caraway oil (Carum carvi L.), specifically developed by Dr. Willmar Schwabe (often referred to by the code WS 1520). It is primarily indicated for the treatment of functional gastrointestinal disorders, including functional dyspepsia and irritable bowel syndrome (IBS). The mechanism of action is multi-targeted: peppermint oil acts as a local spasmolytic on the smooth muscles of the gastrointestinal tract by blocking voltage-gated calcium channels, while caraway oil exerts carminative effects and acts synergistically to reduce bloating, flatulence, and abdominal pain. The formulation is typically enteric-coated to bypass the stomach and target the intestines, thereby reducing the risk of gastrointestinal reflux or heartburn associated with peppermint oil.

Brand names
GaspanMenthacarin
Other names
Peppermint oil and caraway oil combination
02

Targets

LTCC (Voltage-gated calcium channel (L-type))

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