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PeptOss
- Development stage
- Preclinical
- Lead developer
- Bone Sci Bio
- Modality
- Peptides, Hydrogel Systems → Drug Delivery Systems
- Administration
- Local, Implantation, Topical
01
Overview
**PeptOss** is an investigational bone regeneration product being developed by Bone Sci Bio for orthopedic and dental applications. It is a **biologic peptide-based biomaterial** built around the proprietary short peptide **PFD5**, invented at Ben-Gurion University of the Negev. PFD5 is designed to mimic proteins of the bone extracellular matrix and self-assemble into a hydrogel; when combined with calcium phosphate particles, the material promotes biomineralization of hydroxyapatite to support bone formation and repair. The platform is also intended to function as a local sustained-delivery matrix for agents such as antibiotics or chemotherapeutics over several weeks. The lead stated indication is **peri-implantitis**, with additional proposed applications including bone strengthening in osteoporosis and local chemotherapy delivery for osteosarcoma.
- Brand names
- PeptOss
- Other names
- PFD5PFD-5PFD 5
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