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Perakizumab is a human monoclonal antibody that targets interleukin-17A (IL-17A), acting as an IL-17A inhibitor. It was developed by Roche for the treatment of psoriatic arthritis. The drug works by binding to and neutralizing IL-17A, a pro-inflammatory cytokine implicated in the pathogenesis of several autoimmune diseases, including psoriatic arthritis. Perakizumab advanced to phase 1 clinical trials but development was discontinued after this stage[1][2][4].
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